Mesolite catalyzed one pot synthesis of quinoline-3-carbonitrile derivatives

Authors

Ganesh Pawar Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad (M.S.), 431004, India.

Machhindra Lande Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad (M.S.), 431004, India.

Rameshwar Magar Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad (M.S.), 431004, India.

Abstract:

Natural mesolite type zeolite was collected, modified by sulfuric acid treatment and characterized by using Powder-X ray diffraction (XRD), Scanning electron microscopy (SEM), Energy dispersive spectroscopy (EDS), Fourier transform infrared spectroscopy (FT-IR).Temperature programmed ammonia desorption (NH3-TPD), Brunauer-Emmer-Teller (BET) surface area analysis. Modified dealuminated mesolite shows an efficient catalytic activity for the one-pot synthesis of quinoline-3-carbonitrile derivatives, via three-component cyclocondensation of benzaldehyde, malononitrile and aniline. The present method offers several advantages over the reported methods like simple and inexpensive modification of the catalyst, mild reaction conditions and easy separation of the catalyst, simple work-up procedures, non-chromatographic separation and purification of desired product, excellent yield and reusability of the catalyst.

Upgrade to premium to download articles

Already have an account?login

similar resources

An efficient one-pot, three-component synthesis of indeno[1,2-b]quinoline-9,11(6H,10H)-dione, acridine-1,8(2H,5H)-dione and quinoline-3-carbonitrile derivatives from enaminones.

An efficient one-pot, three-component method for the preparation of indeno[1,2-b]quinoline-9,11(6H,10H)-dione, acridine-1,8(2H,5H)-dione and various multi-substituted quinoline-3-carbonitrile derivatives has been developed through the Michael addition to enaminones, which was achieved by both microwave irradiation and conventional heating.

full text

One-pot Synthesis of Polysubstituted Indolizine Derivatives

An efficient approach to the synthesis of 1,2,3-trisubstituted indolizines is described via one-pot reactions of pyridine and dialkyl acetylendicarboxylate in the presence of ethyl 2-chloroacetoacetate in MeOH at room temperature. The corresponding 1, 2, 3-trisubstituted indolizines may be useful building blocks for the construction of complex indolizine derivatives.

full text

One-pot synthesis of 2-amino-3-cyanopyridine derivatives catalyzed by zinc zirconium phosphate in solvent-free conditions

A simple and efficient procedure for the synthesis of 2-amino-3-cyanopyridines from aldehydes, ketones, malononitrile, and ammonium acetate via one-pot reaction is reported. Zinc zirconium phosphate (ZPZn) nanoparticles were used as a convenient and efficient catalyst for this multicomponent reaction (MCR) under solvent-free conditions, and fair to excellent yields were achieved. The catalyst w...

full text